Carnosine CAS 305-84-0 L-Carnosine Powder
Product Description
Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is present in all vertebrates. Carnosine has a number of beneficial antioxidant properties. For example, carnosine scavenges reactive oxygen species (ROS) as well as alpha-beta unsaturated aldehydes created by peroxidation of fatty acid cell membranes during oxidative stress. Carnosine can oppose glycation, and it can chelate divalent metal ions. Carnosine alleviates diabetic nephropathy by protecting podocyte and mesangial cells, and can slow down aging. Its component, the amino acid beta-alanine, is particularly interesting as a dietary supplement for athletes because it increases muscle carnosine, and improves effectiveness of exercise and stimulation and contraction in muscles. Carnosine is widely used among athletes in the form of supplements, but rarely in the population of cardiovascular or diabetic patients. Much less is known, if any, about its potential use in enriched food.
BASIC ANALYSIS
| Item of Analysis | Specification | Results |
| Appearance | Off-white or white powder | White power |
| Identification | Consistent with the reference substance main peak retention time | Conforms |
| Specific rotation [α]D20 | +20.0°to +22.0° | +21. 1 ° |
| Heavy metals | ≤ 10ppm | Conforms |
| H | 7.5 to 8.5 | 8.2 |
| Loss on drying | ≤ 1.0% | 0. 18% |
| Residue on ignition | ≤ 0. 10% | 0.04% |
| Lead | ≤ 3ppm | Conforms |
| Arsenic | ≤ 1ppm | Conforms |
| Mercury | ≤ 0. 1ppm | Conforms |
| Cadmium | ≤ 1ppm | Conforms |
| Melting point | 250.0C to 265.0C | 254.4C to 255.8C |
| Hydrazine | ≤ 2ppm | Conforms |
| Bulk density | ------- | 0.25g/ml |
| Tapped density | ------- | 0.50g/ml |
| L-Histidine | ≤ 0.3% | 0.08% |
| Assay (HPLC) | 99.0% to 101.0% | 99.7% |
| Total aerobes counts | ≤ 1000cfu/g | Conforms |
| Yeast and Mould | ≤ 100cfu/g | Conforms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
Function
Antioxidant Effect
- Neutralizes free radicals, reduces oxidative stress damage to cells, and protects cell health.
Anti-aging effects
- Slows down the skin aging process, improves skin elasticity and firmness, and reduces wrinkles and fine lines.
Anti-glycation effect
- Inhibit glycation reactions, reduce the formation of advanced glycation end products (AGEs), and reduce the risks associated with aging and chronic diseases.
Improved Athletic Performance
- Buffers lactic acid accumulation, delays fatigue, improves endurance and strength, suitable for athletes and fitness enthusiasts.
Neuroprotective Effects
- May improve cognitive function and slow the progression of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.
Promote wound healing
- Promotes cell regeneration and repair, aids wound healing and tissue repair.
Moisturizing effect
- Maintains skin moisture balance, strengthens skin barrier function, and keeps skin soft and smooth.
Soothing and anti-inflammatory effects
- Relieves skin irritation and redness, suitable for sensitive skin.
Application
Application of Carnosine in Cosmetics
Anti-aging skincare products
- Creams, serums and eye creams designed to enhance the skin’s youthful appearance and reduce the appearance of wrinkles and fine lines.
Anti-glycation skin care products
- Products targeting uneven skin tone and sagging skin help inhibit glycation and reduce the formation of AGEs.
Moisturizing products
- Moisturizing creams, masks and lotions, etc., suitable for dry skin to help maintain moisture balance.
Repair skin care products
- Wound repair cream and sensitive skin care products to promote wound healing and skin repair.
Soothing skincare
- Sensitive skin care products and soothing creams to help reduce skin irritation and redness.
Application of Carnosine in the field of health food
Antioxidant supplements
- Antioxidant nutritional supplement designed to enhance overall health and reduce oxidative stress.
Sports Nutrition Supplements
- Sports drinks and energy gels to help increase endurance and strength, and improve athletic performance.
Cognitive Health Supplements
- Nutraceuticals targeting brain health and cognitive function may help slow the progression of neurodegenerative diseases.
Diabetes Management Foods
- A health food that helps improve blood sugar control and is suitable for diabetic patients.
Recovery and Recovery Supplements
- A health food that promotes wound healing and tissue repair, suitable for use during the recovery period.
