Cosmetic Grade CAS 497-30-3 Ergothioneine L-Ergothioneine Powder
roduct Description
Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.
Ergothioneine, or EGT for short, is a naturally occurring sulfur-containing amino acid with a unique chemical structure. Initially, the ingredient was isolated from the ergot fungus in 1909. It is mainly found in certain fungi and bacteria. Ergothioneine is also found in human tissues and organs such as red blood cells, bone marrow, liver, kidneys, and eyes. However, the human body cannot synthesize it on its own and can only obtain it through diet. Mushrooms are the main dietary source.
Ergothioneine is known for its strong antioxidant properties, which can scavenge free radicals and chelate various divalent metal cations. It interacts with other natural antioxidant defense systems in the body. In addition, the ingredient has anti-inflammatory and cell-protective effects. Therefore, it has been widely used in food, medicine, and cosmetics.
Ergothioneine Sources From
- Edible fungi. The precursor hercynine required for synthesizing ergothioneine can be produced in edible fungi such as Boletus edulis, mushrooms, and Coprinus comatus.
- Animal tissues. This ingredient is also present in certain tissues and organs of mammals, especially in red blood cells.
BASIC ANALYSIS
|
Items |
Specifications | Results |
| Appearance | White or almost white powder | Confirm |
| Odor | Characteristic | Confirm |
| Water | ≤2.0% | 0.12% |
| Assay(HPLC) | 95.0%-100.0% | 99.8% |
| Ash | ≤1.0% | 0.5% |
| Heavy Metal | ≤10 ppm | Confirm |
| As | ≤0.5ppm | Confirm |
| Pb | ≤0.5ppm | Confirm |
| Cd | ≤0.5ppm | Confirm |
| Hg | ≤0.1ppm | Confirm |
| Total plate count | ≤750 cfu/g | Confirms |
| Yeast&Mold | ≤100 cfu/g | Confirms |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Staphylococcus aureus | Negative | Negative |
Benefits
- Antioxidant effect
This ingredient is a powerful antioxidant. It can remove free radicals, whiten, anti-aging, anti-radiation, maintain DNA synthesis and normal cell growth, and other physiological functions.
- Anti-inflammatory and anti-acne
Studies have shown that it can be anti-inflammatory in skin cells, helping to reduce inflammation and acne.
- Anti-aging
Due to its high antioxidant capacity, it can delay aging, reduce or even prevent protein saccharification, improve facial contours, and prevent or improve the appearance of orange peel lines.
- Whitening effect
It can hinder pigmentation and deposition and whiten the skin.
- Sunscreen effect
It can minimize the formation of reactive oxygen species and protect cells from radiation damage. It can be added to cosmetics as a skin protectant for developing outdoor and protective skin care products.
- Synergistic effect
EGT can regulate the redox reaction in cells and participate in the energy regulation in cells. Combined with other ingredients, it can enhance the efficacy of other ingredients and achieve synergistic effects.
- Protect mitochondria
EGT can enter mitochondria and cell nuclei, protect mitochondria from oxidative damage, and directly remove reactive oxygen free radicals, thus removing aging factors from the root.
- Anti-photoaging
It is mainly anti-ultraviolet, inhibiting UV-induced peroxidation and inflammatory factor expression.
- Anti-glycation
It can reduce the production of advanced glycation end products (AGEs). It helps maintain skin elasticity and health.
- Prevent DNA damage
It helps prevent mitochondrial DNA damage and maintain cell function and skin health.
These properties of ergothioneine make it a popular ingredient in skincare products, especially anti-aging and sunscreen products.
Other Benefits
- Eye protection
- Cardiovascular health
- Muscle repair
- Treat inflammation
- Prevent UV Damage
- Prevent neurodegenerative diseases
Studies have shown that EGT can break through the blood-brain barrier, and can regulate neuronal differentiation, neurogenesis, and microglial activation, and can also prevent neurotoxicity caused by pathogenic proteins or chemicals. The latest research shows that long-term supplementation of EGT has a positive effect on the prevention of neurodegenerative diseases such as senile dementia and Alzheimer’s disease.
Application
- Skin care products: Mainly whitening, anti-wrinkle, anti-allergic, anti-acne, anti-aging and other effects. And protective skin care products.
- Supplements: Enhance immunity, prevent Alzheimer’s disease, assist in lowering blood sugar and other functional foods or drinks
- Drugs: It can treat inflammation, senile dementia, eye drops, and other drugs.
- Food: In 2017, the European Food Safety Authority used it as a new resource food in the diet of infants, pregnant women, and lactating women
Ergothioneine Dosage: 0.1%-1.0%
How Does EGT Work?
- Effective for different organs.
EGT is a water-soluble amino acid molecule that can be delivered to red blood cells, bone marrow, liver, kidneys, eyes and other tissues and organs through the OCTN1 transporter.
- Enter the cell membrane.
EGT is a membrane-impermeable substance that requires specific transporters to enter cells. The OCTN1 transporter is distributed on the cell membranes of different tissues, especially in the kidney, trachea, bone marrow, and skeletal muscle. In addition, the mitochondria also contain OCTN1 protein, so EGT can enter the mitochondria to play an antioxidant role very easily.
Gmo statement
We hereby declare that, to the best of our knowledge, this product was not produced from or with GMO plant material.
Ingredient statement
Statement Option #1: Pure Single Ingredient
This 100% single ingredient does not contain or use any additives, preservatives, carriers and/or processing aids in its manufacturing process.
Statement Option #2: Multiple Ingredients
Must include all/any additional sub ingredients contained in and/or used in its manufacturing process.
Gluten free statement
We hereby declare that, to the best of our knowledge, this product is gluten-free and was not manufactured with any ingredients containing gluten.
(Bse)/ (Tse) Statement
We hereby confirm that, to the best of our knowledge, this product is free of BSE/TSE.
Cruelty-free statement
We hereby declare that, to the best of our knowledge, this product has not been tested on animals.
Kosher statement
We hereby confirm that this product has been certified to Kosher standards.
Vegan Statement
We hereby confirm that this product has been certified to Vegan standards.
Food Allergen Information
| ALLERGENS | PRESENCE | ABSENCE | PROCESS COMMENT |
| Milk or milk derivatives | No | Yes | No |
| Egg or egg derivatives | No | Yes | No |
| Fish or fish derivatives | No | Yes | No |
| Shellfish, crustaceans, mollusks & their derivatives | No | Yes | No |
| Peanuts or peanut derivatives | No | Yes | No |
| Tree nuts or their derivatives | No | Yes | No |
| Soy or soy derivatives | No | Yes | No |
| Wheat or wheat derivatives | No | Yes | No |
Trans Fat
This product does not contain any trans fats.
