High Purity NAD β-Nicotinamide Adenine Dinucleotide NAD+ Cas 53-84-9
Product Description
β-Nicotinamide adenine dinucleotide (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH (Cat# N-035) which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.
What is NAD+？
NAD is short for nicotinamide adenine dinucleotide.
It is a coenzyme and exists in NAD+ form and NADH form.
Here we talk about NAD+.
Now, there is a small power plant in every cell of your body. It is called the mitochondria.
Mitochondria are the source of all energy in the body. From lifting weights, blinking, digesting food to the heartbeat, everything relies on mitochondria.
NAD+ is the primary source to keep mitochondria activity.
When we were young, our bodies were full of NAD+. We get all the NAD+ we want.
But as we age, our NAD+ levels begin to fall like stones. Every 20 years, your NAD+ level drops by 50%.
BASIC ANALYSIS
| Test items | Specifications | Test Method | Results |
| Appearance | White to off-white powder | Visual inspection | White powder |
| Solubility | Soluble in water | Visual inspection | Soluble in water |
| Purity（%） | >99.0% | HPLC | 99.23 |
| Assay（%） | 98.0%-102.0% | HPLC | 99.58 |
| Water content（%） | <8% | Karl Fischer | 7.00 |
| Pb ( ppm ) | <0.5 | GB 5009.12 | Conform |
| As(ppm) | <0.5 | GB 5009.11 | ND |
| Hg ( ppm ) | <0.5 | GB 5009.17 | ND |
| Cd ( ppm ) | <0.5 | GB 5009.15 | ND |
| Total microbial count | <300 CFU/g | GB 4789.2 | Conform |
| E.coil | Not Detected | GB 4789.38 | ND |
| Yeast and mold | <10 CFU/g | GB 4789.15 | ND |
| Salmonella | Not Detected | GB 47894 | ND |
| Staphylococcus aureus | Not Detected | GB 4789.10 | ND |
Function
Nicotinamide Adenine Dinucleotide (NAD) is an important coenzyme that plays a key role in cellular energy metabolism and redox reactions. Here are some professional introductions to NAD:
- Cellular energy metabolism: NAD is a key factor in converting nutrients in food into cellular energy. It participates in processes such as glycolysis, anaerobic respiration, and aerobic respiration within cells, helping to generate the required adenosine triphosphate (ATP) energy supply.
- Antioxidant effect: NAD also plays an important antioxidant role in cells. It can work with antioxidant enzymes to scavenge free radicals and other harmful oxidants, reduce oxidative damage to cells, help maintain cell health and delay the aging process.
- DNA repair: NAD is also involved in the process of DNA repair, helping to correct damage in DNA molecules and maintain the integrity of the cell's genetic information.
- Enhance immune function: NAD promotes the activity and function of immune cells and supports the immune system's response to viruses, bacteria and other pathogens.
- Improve cardiovascular and cerebrovascular health: NAD has been proven to improve cardiovascular and cerebrovascular health. It helps enhance the elasticity and function of blood vessel walls and improves blood circulation, thereby reducing the risk of cardiovascular and cerebrovascular diseases.
In addition, NAD has been found to be related to many other physiological processes and diseases, such as anti-cancer effects, neurodegenerative diseases, diabetes, depression, etc. However, using NAD as a supplement or pharmaceutical treatment requires more research and clinical validation.
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