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Hot Selling Cosmetic Peptide Copper Tripeptide-3 CAS 682809-81-0 AHK -Cu

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  • Product Name: AHK -Cu
  • INCI Name: Copper Tripeptide-3
  • Cas No: 682809-81-0
  • Molecular Formula: C₁₅H₂₄CuN₆O₄
  • Molecular Weight: 415.12
  • Appearance: Blue powder
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    Product Description

    • In the global personal care market, "scalp-care-as-skincare" and "scientific anti-hair loss" have emerged as the fastest-growing premium sectors. Traditional anti-hair loss actives often come with consumer hurdles, such as sudden shedding phases upon withdrawal or poor formulation aesthetics. AHK-Cu (Copper Tripeptide-3) is a highly precise biomimetic signal peptide. Engineered specifically to stimulate hair follicle proliferation, extend the hair growth cycle, and restructure the scalp's dermal matrix, it is rapidly becoming the technological core of premium hair growth serums, scalp treatments, and anti-aging hair care lines.
    • Primary Biological Targets: Dermal Papilla Cells (DPCs), Scalp Fibroblasts
    • Core Applications: Anti-hair loss targeted serums, scalp priming tonics, eyelash/brow growth boosters, high-performance scalp-aging defense creams.
    • As a premier high-activity peptide raw material supplier, we provide high-purity, batch-stable bulk AHK-Cu to help your brand seize the technological edge in the scientific hair care market.

    Basic Analysis

    Item

    Standard

    Result

    Appearance

    Blue powder

    Complies

    Identity by ESI-MS

    Theoretical MW:415.12

    Complies

    Purity (HPLC)

    ≥95.0%

    98.30%

    Water (K.F.)

    ≤5.0%

    4.66%

    Cu⁺ Content

    8.0-16.0%

    12.13%

    AHK Content

    ≥65.0%

    70.13%

    Chloride Content (IC)

    ≤10.0%

    8.59%

    pH (1% Water Soln.)

    6.0-8.0

    7.52

    Solubility

    ≥100mg/ml(H₂O)

    Complies

    Lead (mg/kg)

    ≤10

    <10

    Arsenic (mg/kg)

    ≤2

    <2

    Mercury (mg/kg)

    ≤1

    <1

    Cadmium (mg/kg)

    ≤5

    <5

    Total plate count (cfu/g)

    ≤1000

    Complies

    Yeast & mould (cfu/g)

    ≤100

    Complies

    Benefits

    While AHK-Cu belongs to the same copper peptide family as the famous skin-remodeling peptide GHK-Cu (Copper Tripeptide-1), the integration of Alanine into its peptide sequence gives it a significantly higher binding affinity for hair follicle structures and scalp tissues:

    • Activating Dermal Papilla Cells & Elongating the Anagen Phase

    Dermal papilla cells act as the "command center" regulating hair thickness and growth. AHK-Cu significantly stimulates the proliferation of these cells, preventing hair follicles from prematurely entering the catagen (regression) phase. By extending the Anagen (growth) phase, it reduces daily fallout from the root.

    • Upregulating Extracellular Matrix (ECM) Synthesis

    Scalp aging leads to follicle miniaturization. AHK-Cu efficiently prompts scalp fibroblasts to synthesize Type I Collagen and Elastin. This thickens the surrounding dermal tissue, providing a sturdier "anchoring matrix" for hair roots and preventing premature physical shedding.

    • Mitigating Hair-Loss Triggers (Mild DHT Interruption)

    In vitro evaluations indicate that AHK-Cu exhibits an inhibitory tendency toward 5-alpha reductase—the enzyme responsible for generating Dihydrotestosterone (DHT), the primary culprit behind androgenetic alopecia. It delivers a gentle, drug-free alternative without creating resistance or dependency.

    • Optimizing Scalp Microcirculation

    The copper complex promotes the expression of vascular endothelial growth factors, stimulating the micro-capillary network of the scalp. This delivers a rich, uninterrupted supply of oxygen and vital nutrients directly to hungry follicles.

    • Proven "Hair Growth" Benchmark Performance

    In comparative tissue assays, AHK-Cu demonstrates exceptional efficacy in accelerating the growth of follicular epithelial cells, making it a globally recognized, safe alternative to traditional chemical hair stimulants.

    • Zero Rebound or Radical Shedding Phases

    Unlike harsh pharmaceutical alternatives that can cause localized itching, redness, or a massive "shedding shock" if discontinued, AHK-Cu is entirely biocompatible, non-irritating, and exhibits a superior safety profile.

    Application

    • Premium Anti-Hair Loss Target Serums

    Perfect as a hero active paired with scalp-massaging rollerballs or dropper mechanisms, targeting receding hairlines and thinning crowns.

    • Scalp-Clinic Therapy Ampoules

    Designed for professional salons or clinical care lines, ideal for post-treatment application or micro-needling protocols to accelerate scalp barrier recovery and follicle awakening.

    • Eyelash & Brow Growth Boosters

    Capitalizing on its gentle, non-mucosal irritating nature to develop clean, safe, and fast-acting lash-lengthening products.

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