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Hydroxypropyl gamma cyclodextrin

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  • Product Name: Hydroxypropyl gamma cyclodextrin
  • Another name: hydroxypropyl - γ - cyclodextrin; hydroxypropyl - gamma - cyclodextrin;
  • Abbreviation: HP - γ - CD
  • CAS NO.: 128446-34-4
  • Molecular weight: 1297.2 + n. (58.1)
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    Products Description

    Hydroxypropyl- gamma-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.

    Characteristics

    Hydroxypropyl gamma cyclodextrin dissolves large molecules, such as cholesterol, for cell culture. It is similar to betacyclodextrin, but can dissolve larger molecules.

    Application

    The water solubility of hydroxypropyl - γ - cyclodextrin was further increased to 80g / 100ml (25 ℃). At the same time, the hydroxypropyl - γ - cyclodextrin was no longer a single pure product, but a mixture of multiple substitutions. It was not easy to form inclusion complex crystal precipitation when it was combined with guest molecules. In general, hydroxypropyl - γ - cyclodextrin had higher water solubility and stronger anti-oxidation ability The ability of crystallization. The solubility of γ - cyclodextrin in water is 23.2g/100ml (25 ℃), and its application is limited in some cases.

    Basic Analysis

    ITEMS CRITERIA
    Appearance White or almost white powder;Odorless,slightly sweet;Freely soluble in water,soluble in ethanol,almost insoluble in acetone.
    Water solution pH pH5.0~8.5
    Light-absorbing impurities Between 230 and 350 nm,the absorbance is NMT 0.5; and between 350 and 660 nm, the absorbance is NMT 0.5.
    Water ≤10.0%
    Gamma Cyclodextrin ≤1.5%
    Residue on ignition ≤0.2%
    Heavy Metal ≤10ppm
    Propylene glycol ≤0.5%
    Assay ≥95%
    Hydroxypropoxyl content 17.5%~29.1%
    The total aerobic microbial count ≤1000cfu/g
    The total combined moulds and yeasts count ≤100cfu/g
    Escherichia coli Absence
    Bacterial Endotoxins Test According to preparation needs

    Gmo statement

    We hereby declare that, to the best of our knowledge, this product was not produced from or with GMO plant material.

    Ingredient statement

    Statement Option #1: Pure Single Ingredient
    This 100% single ingredient does not contain or use any additives, preservatives, carriers and/or processing aids in its manufacturing process.
    Statement Option #2: Multiple Ingredients
    Must include all/any additional sub ingredients contained in and/or used in its manufacturing process.

    Gluten free statement

    We hereby declare that, to the best of our knowledge, this product is gluten-free and was not manufactured with any ingredients containing gluten.

    (Bse)/ (Tse) Statement

    We hereby confirm that, to the best of our knowledge, this product is free of BSE/TSE.

    Cruelty-free statement

    We hereby declare that, to the best of our knowledge, this product has not been tested on animals.

    Kosher statement

    We hereby confirm that this product has been certified to Kosher standards.

    Vegan Statement

    We hereby confirm that this product has been certified to Vegan standards.

    Food Allergen Information

    ALLERGENS PRESENCE ABSENCE PROCESS COMMENT
    Milk or milk derivatives No Yes No
    Egg or egg derivatives No Yes No
    Fish or fish derivatives No Yes No
    Shellfish, crustaceans, mollusks & their derivatives No Yes No
    Peanuts or peanut derivatives No Yes No
    Tree nuts or their derivatives No Yes No
    Soy or soy derivatives No Yes No
    Wheat or wheat derivatives No Yes No

    Trans Fat

    This product does not contain any trans fats.

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