Apigenin, a bioflavonoid found in a variety of plants, has received a lot of attention for its numerous health benefits. From preventing cancer to relieving anxiety, this natural compound has a range of benefits to promote overall health. In this article, we delve into the incredible potential of apigenin, learning about its properties, natural sources, and its role in disease prevention.
At Aogubio, a company specializing in the production and distribution of pharmacologically active substances, raw materials and plant extracts, we recognize the importance of apigenin and its impact on human health. Our goal is to provide products to the pharmaceutical, food, nutraceutical and cosmetic industries that harness the power of apigenin to support a healthy lifestyle.
Apigenin is classified as a bioactive flavonoid with a range of health benefits. One of its key properties is its antioxidant effect, which helps fight oxidative stress and protect cells from damage. By reducing the harmful effects of free radicals, apigenin promotes overall health and maintains the health of vital organs.
Plus, apigenin has anti-inflammatory properties, making it a valuable addition to any natural health routine. By reducing inflammation in the body, apigenin can help relieve symptoms associated with chronic inflammation and support a healthy immune system.
Recent studies have also found compelling evidence linking apigenin to cancer prevention. This powerful compound has shown promising anticancer properties, inhibiting the growth of cancer cells and reducing the risk of tumor formation. By incorporating apigenin-rich foods into your diet, you can take an important step toward optimal health and minimize your risk of various types of cancer.
In addition, apigenin has been found to have anxiolytic effects, which may relieve anxiety and promote better mental health. This natural compound has the potential to regulate hormones and affect neurotransmitters, helping individuals combat symptoms of anxiety disorders and improve their overall health.
When incorporating apigenin into your diet, there are several natural sources to consider. Chamomile tea, known for its calming properties, contains high amounts of apigenin. Other vegetables and herbs, such as parsley, celery, and thyme, also contain apigenin and are excellent additions to a healthy diet rich in apigenin.
It's worth noting that while apigenin is stable when consumed as part of the diet, it can be unstable when isolated from sources. Therefore, combining whole foods with natural sources of apigenin is the best way to effectively reap its benefits.
At Aogubio, our goal is to harness the power of apigenin by providing high quality nutraceuticals and supplements. Our products are carefully formulated to ensure the correct dosage and optimal delivery of apigenin, maximizing its health benefits to our customers.
The effects of apigenin on mental health is another aspect worth exploring. Its ability to reduce anxiety and affect immune health can play an important role in promoting overall health and cognitive function. By incorporating apigenin into your daily life, you can support mental health and enhance cognitive performance.
Overview of potential apigenin health benefits:
- Reduced Inflammation
- Reduced Risk of Cancer
- Enhanced NAD Levels
- Reduced Feelings of Anxiety
- Reduced Feelings of Depression
- Lower Cholesterol and Obesity Prevention
- Protection from Oxidative Stress
- Relief from Rheumatoid Arthritis
- Treatment of Autoimmune Disease
- Prevention of Neurodegenerative Disease
- Treatment of Migraines
- Improved Sleep
How does apigenin work?
Animal studies suggest that apigenin may impede genetic mutations occurring in cells that are exposed to toxins and bacteria.Apigenin may also play direct roles in the removal of free radicals, inhibition of tumor growth enzymes, and induction of detoxification enzymes such as glutathione. Apigenin’s anti-inflammatory ability may also explain its effects on mental health, brain function, and immunological response,though some large observational studies don’t support this conclusion with respect to metabolic conditions.
Remember to always consult a healthcare professional before making any major changes to your diet or starting a new supplement regimen. They can provide valuable guidance based on your specific needs and health goals.
Among the many directions of apigenin's effects, there are four main areas to be distinguished:
Neuroprotective function
Dietarily available apigenin can prevent the activation of microglia and exhibit a protective effect against or delay the onset of Alzheimer's disease. The neuroprotective effect of apigenin has been demonstrated in several studies in mice. Supplementation with apigenin in a mouse model of the disease, yielded improvements in memory and learning deficits and a reduction in fibrillar amyloid deposits with reduced levels of insoluble β-amyloid peptide, which is thought to be crucial in the onset and progression of Alzheimer's disease. In addition, it was shown that apigenin caused restoration of the ERK/CREB/BDNF pathway, which is involved in memory function and is particularly affected by Alzheimer's disease. In another study on mice with amnesia, apigenin improved memory and spatial learning performance.
Antitumor function
In animal experiments, it was noted that the use of apigenin before and during exposure to carcinogens, reduced the risk of developing cancer compared to a control group in which exposure to carcinogens was not accompanied by apigenin consumption. Selective enhancement of tumor cell apoptosis and inhibition of metastasis were also observed. The mechanisms of action responsible for this are similar to those of other common flavonoids, namely antioxidation, inhibition of inflammation and cell cycle progression, and support of hepatic detoxification.
In addition, apigenin improves autophagy - the body's natural process for recovering "building blocks" at the cellular level by "recycling" incorrectly copied cells (which can turn cancerous).
Anti-aging function
Through its anti-inflammatory effects, apigenin is an inhibitor (a chemical that causes a decrease in the rate of chemical reaction) of the CD38 protein - whose production (increasing with age) is linked to the body's response to inflammation, and whose increased presence drains the body's supply of NAD+ - an essential resource needed for the correct regeneration of DNA and cells (whose levels decrease with age) - resulting in accelerated aging.
Regulatory and anabolic function
Apigenin positively modulates GABA(A) receptors[1], resulting in a calming and quieting effect. It also lowers basal cortisol (a key contributor to chronic stress)
Post time: Aug-01-2023
