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Sepiwhite MSH Powder Ingredients Analysis: Understanding the Science behind Whitening Agents

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  • INCI: Undecylenoyl phenylalanine
  • Cas No: 175357-18-3
  • Appearance: White powder
  • Solubility: Water soluble at pH 7, otherwise insoluble in water. Miscible in water. Soluble in alcohol and oil.
  • Recommended Usage Rate: 0.2 – 2%
  • pH: (1% solution in water) 4.0
  • Standard: GMP, Kosher, HALAL, ISO9001, HACCP
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    • Introduction:

    Aogubio is a renowned company specializing in the production and distribution of pharmacologically active substances, raw materials, plant extracts, and nutraceuticals. Their dedication extends to creating supplements for human use, pharmaceutical products, as well as offerings for the food, nutritional, and cosmetic industries. Among their exceptional range of products, Sepiwhite MSH Powder stands out as a highly effective whitening agent in the cosmetics sector. In this article, we will analyze the ingredients of Sepiwhite MSH Powder and explore its mechanism of action.

    • Sepiwhite MSH Powder:

    Undecylenoylphenylalanine, also known as amide, serves as the key ingredient in Sepiwhite MSH Powder. This potent compound acts as a melanotropic hormone (α-MSH) receptor antagonist, directly targeting the biochemical reactions involved in melanin formation triggered by α-MSH. By intercepting the signals responsible for melanin production, Sepiwhite MSH Powder effectively controls the levels of α-MSH (melanocyte stimulating hormone) and regulates melanin synthesis.

    • Mechanism of Action:

    Melanin, the pigment responsible for skin color, is produced by specialized cells known as melanocytes. The activity of an enzyme called tyrosinase plays a crucial role in melanin synthesis. Sepiwhite MSH Powder inhibits the activity of this enzyme, thereby reducing the formation of melanin. By controlling the production of α-MSH, which stimulates melanocytes, Sepiwhite MSH Powder effectively suppresses melanin synthesis, resulting in a visible skin whitening effect.

    • Cosmetic Application:

    Sepiwhite MSH Powder finds its primary application in the cosmetic industry as a whitening agent. The ability to regulate melanin production and inhibit tyrosinase activity makes it a valuable ingredient in various skin lightening products. Its precise mechanism of action provides a safer alternative to traditional skin-lightening ingredients, which often come with potential side effects. Sepiwhite MSH Powder allows for precise control over the skin's pigmentation, resulting in a more even and luminous complexion.

    • Benefits:

    The key advantages of Sepiwhite MSH Powder lie in its effectiveness and versatility. Its ability to target melanin synthesis at various stages, intercept signals, and inhibit tyrosinase makes it an ideal choice for whitening products. Unlike some other whitening agents, Sepiwhite MSH Powder offers a reliable and consistent whitening effect, allowing consumers to achieve their desired skin tone without compromising on safety and efficiency.

    • Safety Profile:

    When it comes to skin-lightening products, safety is of paramount importance. Sepiwhite MSH Powder has been extensively tested for its safety profile. The compound has shown excellent skin compatibility and minimal risk of skin irritation. This makes it suitable for both topical and long-term use in cosmetics. However, it is always advisable to conduct a patch test before incorporating any new product into your skincare routine.

    • Conclusion:

    In summary, Sepiwhite MSH Powder, manufactured and distributed by Aogubio, stands out as a highly effective whitening agent in the cosmetic industry. Its primary ingredient, undecylenoylphenylalanine, acts as a melanotropic hormone receptor antagonist, controlling the biochemical reactions involved in melanin synthesis. By inhibiting tyrosinase activity and intercepting melanin production signals, Sepiwhite MSH Powder offers a reliable and safe solution for achieving a brighter, more even complexion. As with any new cosmetic product, it is important to perform a patch test and consult a dermatologist if you have any concerns. Embrace the benefits of Sepiwhite MSH Powder and unlock the secret to a radiant and luminous skin tone.

    Products Description

    Sepiwhite™ MSH is an excellent skin lightener and brightener suitable for all skin types and ethnicities that promotes a more uniform and radiant complexion with results in as little as seven days. Studies have demonstrated an increase in skin luminosity and decrease in the number and color of hyperpigmented spots, and it can be combined with other active ingredients, such as niacinamide or AHAs. Sepiwhite™ MSH is a lipoaminoacid or vectorized essential amino acid developed from phenylalanine, an amino acid involved in melanin synthesis. MSH is an alpha-melanocyte-stimulating hormone (MSH) receptor agonist developed from this amino acid that inhibits the process of melanin synthesis from the hypothalamus to produce a reduction in melanic pigments in skin cells.

    Benefits

    • Promotes a more uniform and more radiant complexion
    • Promotes reduction of number and color of age spots
    • Demonstrated effectiveness for all skin types and ethnicities
    • Promotes a more even skin tone
    • Reported visible increases in skin luminosity and brightness
    • ECOcert
    • Preservative free, paraben free phthalate free
    • Readily biodegradable
    • Non-phototoxic

    Application

    • Anti-aging products for face and body, including gels, emulsions, and toners
    • Daily skin rejuvenating products, like sera, targeted treatments, and moisturizers
    • Revitalizing products such as toners, gels, masks, and eye products
    • Skin lightening make-up removers
    • Pressed and loose mineral make-up powders, including foundations and highlighters

    Formulation Guide

    • Use 0.2% in combination with another brightener, otherwise up to 2% in the heated water or heated oil phase of a formulation at more than 60°C (140°F).
    • In a product with pH 5 or lower, incorporate into any type of formula.
    • In a product above pH 5, but below 6.2, can incorporate with the use of up to 20% ethanol. Not the ideal pH range for this ingredient.
    • In a product with pH 6.2 or higher, incorporation into any type of formula is possible.
    • Compatibility & Stability
    • Excellent stability in cosmetic products with no expected color or odor changes
    • Compatible with formulas containing AHA and kojic acid (pH below 5)
    • Compatible with formulas containing arbutin, hydroquinone, niacinamide, and those above pH 7
    • Compatible with sunscreens
    • Suitable for aqueous, hydroalcoholic, or hydroglycolic formulas
    • Suitable for clear, colorless formulas

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