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“The Science Behind Alpha GPC Powder: How it Supports Brain Health”

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  • Another name: Alpha-GPC Powder (L-Alpha-glycerylphosphorylcholine)
  • CAS No.: 28319-77-9
  • MF: C8H20NO6P
  • MW: 257.22
  • Specifications: 99% powder, 85% liquid, 50% granule
  • Appearance: white to off-white powder/transparent liquid/granular
  • Benefits: Improve memory and cognitive, boost muscle and athletic performance,
  • Unit: KG
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    In today's fast-paced and demanding world, maintaining optimal brain function and cognitive ability is more important than ever. Whether you're a student looking to improve your learning capabilities, a working professional seeking to enhance performance, or an older adult hoping to preserve mental acuity, Alpha GPC powder is here to revolutionize the way you think and feel.

    Alpha GPC powder, also known as L-α-glycerol Phosphatidylcholine (GPC), is a natural component that is necessary for the human body. It acts as an intermediate of water-soluble phospholipid metabolites and plays a vital role in the synthesis of neurotransmitters such as acetylcholine and phosphatidylcholine (PC), which are essential for brain function.

    Aogubio is a company specialized in the production and distribution of pharmacologically active substances, raw materials, plant extracts, and nutraceuticals. With a focus on creating supplements for human use, they cater to the pharmaceutical, food, nutritional, and cosmetic industries. Their Alpha GPC powder is a result of extensive research and a commitment to providing high-quality brain-enhancing products.

    This unique compound acts as a cell protectant, supporting the fluidity and integrity of brain cell membranes. It has been found to improve memory and cognitive abilities, making it an invaluable tool in combating brain aging and conditions such as Alzheimer's disease. Alpha GPC powder has rightfully earned the reputation of being the "anti-aging nutrient for the brain."

    The real health benefits of Alpha GPC powder are numerous and diverse. Its ability to directly penetrate the blood-brain barrier allows it to efficiently act on the nervous system of the brain. Let's delve into the specific advantages it offers:

    •  1. Enhanced Neurotransmitter Synthesis: As a choline donor, Alpha GPC powder aids in the rapid synthesis of acetylcholine and phosphatidylcholine in the body. Acetylcholine is a crucial neurotransmitter associated with memory, learning, and attention, making Alpha GPC powder an ideal brain booster.
    •  2. Improved Brain Function: Supplementing with Alpha GPC powder promotes the synthesis of phospholipids in the brain. These compounds serve as signals for the nerve center, providing additional support for learning, memory, cognitive activities, and overall brain function. Moreover, it has been found to enhance sleep quality and muscle activity.

    The health benefits of Alpha GPC powder have been extensively studied in human clinical trials. The results have been remarkable, demonstrating its positive impact on memory, learning, attention, and various cognitive abilities across all age groups.

    For children, Alpha GPC powder has shown to improve learning and behavioral abilities, providing a much-needed boost for young minds. Young adults can benefit from heightened attention and word memory abilities, enabling them to excel in academic or professional settings. Middle-aged and elderly individuals can experience improved cognitive function, emotional well-being, and social abilities, supporting their mental state and quality of life.

    Alpha GPC powder from Aogubio is a safe and effective brain enhancer that offers profound benefits for individuals of all ages. Its natural composition and remarkable ability to support brain health and function make it an essential addition to any daily health regimen.

    When it comes to brain health, don't settle for less than the best. Choose Alpha GPC powder for unparalleled cognitive enhancement and experience the incredible difference it can make in your life. Invest in your brain power today and unlock your full mental potential with the ultimate brain enhancer.

    What is Alpha GPC?

    Alpha-GPC is a member of the phospholipid family, as one of the phosphatidylcholine derivatives, playing an important role in the health of cell membranes.

    alpha-GPC Structural Formula

    The mainly physiological function of Alpha-GPC is to cross the blood-brain barrier and provide the necessary choline for the biosynthesis of acetylcholine and phosphatidylcholine.

    Alpha-GPC is known for its effects on brain health, attention, concentration, and memory generation.

    why do we choose Alpha-GPC, not Beta-GPC?

    Beta-glycerylphosphocholine(Beta-GPC) is also a member of phosphocholines.

    Beta-GPC contributes very little to total GPC(~1%), while Alpha-GPC is hydrolyzed to phosphorylcholine and contributes to the supply of choline needed by the liver and choline needed for myelin synthesis.

    α-GPC β-GPC molecular formula

    How Does Alpha GPC work?

    When the human body absorbs Alpha-GPC, it is decomposed into choline and glycerophosphate under the action of enzymes in the body. Among them, choline participates in the biosynthesis of acetylcholine, which is a kind of neurotransmitter; glycerophosphate is lecithin Derivatives, involved in the synthesis of lecithin.

    The main pharmacological effects of Alpha-GPC include protecting the metabolism of choline; ensuring the synthesis of acetylcholine and lecithin in the nerve membrane, improving blood circulation; improving cognitive and behavioral responses in patients with traumatic brain capillaries.

    Alpha-GPC VS CDP Choline(Citicoline) VS Phosphatidylserine

    From the source, Alpha-GPC can be obtained naturally from soybean lecithin, or it can be made by synthetic route; CDP Choline is mainly synthetic route; phosphatidylserine (PS) can be obtained from soybean lecithin, sunflower lecithin, etc.

    In terms of efficacy, CDP Choline is mainly used as a brain metabolism and neuroactivator, which can promote brain cell respiration, improve brain function, enhance the function of the activation system of the ascending reticular structure, promote recovery, and reduce cerebrovascular resistance; Phosphatidylserine also It is called compound nervonic acid, which is an active substance of cell membrane. Its effect is to improve the function of nerve cells, regulate the conduction of nerve impulses, and enhance the memory function of the brain. Because of its strong lipophilicity, it can quickly enter the brain through the blood-brain barrier after absorption, soothe vascular smooth muscle cells and increase blood supply to the brain.

    The three materials mentioned above are known for their cognitive benefits such as supporting memory, mental performance, and focus.

    Our Alpha-GPC specifications

    • Alpha GPC 50 powder  25kg/Drum
    • Alpha GPC 50% granule  25kg/Drum
    • Alpha GPC liquid 85%  25kg/Drum
    • Alpha GPC powder 99%  1kg/Bag  25kg/Drum
    • Alpha-GPC softgel/Alpha-GPC capsule/Alpha-GPC tablet

    What are the Benefits of taking Alpha GPC?

    Alpha-GPC is a widely used nootropic supplement, main benefits include:

    Protect brain health

    We all know that Alpha GPC is a precursor to acetylcholine, which enhances cholinergic transmission in the brain. Specifically through the mechanism of action Alpha GPC directly increases the synthesis and secretion of acetylcholine, better than any other choline-related compound, affecting choline concentrations system-wide and in the brain.

    Alpha GPC can counteract brain aging by increasing cholinergic receptor sites, restoring the bioavailability of acetylcholine, increasing nerve growth factor receptors in the brain, and slowing down undesirable structural changes in the brain.

    Alpha GPC also works to improve mental performance and improve memory and learning by counteracting the age-related loss of nerve cells and fibers in the brain.

    High doses (1200 mg) of Alpha-GPC are effective in mild to moderate Alzheimer’s disease and work well with standard therapy (acetylcholinesterase inhibitors).

    Boost muscle and athletic performance

    Some preliminary evidence shows that Alpha GPC has the ability to support healthy brain function and the release of somatotrophin (hGH). it also is able to enhance acute growth hormone production and power output during exercise. Increased growth hormone production and power output can increase muscle mass and improve overall metabolic activity, thereby enhancing muscle and athletic performance.

    Studies also report that slightly higher single doses of 600mg-800mg may be more beneficial when Alpha GPC is taken before exercise (such as a pre-workout supplement).

    In summary, Alpha-GPC has two main functions:

    • Central effect: improve dementia; improve learning ability; inhibit the secretion of stress hormones
    • Peripheral effect: promote growth hormone secretion; improve liver function; immunity and repair ability during injury.

    Alpha-GPC Applications:

    In the field of medicine, Alpha-GPC preparations are mainly oral preparations (capsules, tablets). According to statistics, the global GPC preparation market size in 2020 is about 347 million US dollars. Companies like DAEWOONG, CHONG KUN DANG, ITALFARMACO, etc

    In the field of health products, mainly dietary supplements. According to statistics, the global market size of Alpha-GPC-containing health products in 2020 is about 105 million US dollars, Famous brands such as Doctor’s Best, Now Food, etc

    Alpha-GPC Main Countries Regulations:

    USA GRAS
    Alpha-GPC has the status of ‘Generally Recognized as Safe’ (GRAS) as an ingredient in beverages and foods when consumed at a level not to exceed 196.2 mg/person/day.

    In Europe, Alpha GPC is a prescription-strength synthesized medication that is given to Alzheimer’s patients in 1,200 mg doses.

    In Korea, Alpha GPC(Choline alfoscerate) is included in Korean Pharmacopoeia (KPC).

    Recommended dosage:

    Typically, we see that in many brands of GPC supplements, the recommended dosage is 300-600 mg, but for different symptoms and users, a 400-1200mg daily dosage is also suitable.

    package-aogubioshipping photo-aogubioReal package powder drum-aogubi

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